Differentiated care delivery aims to simplify care of people living with HIV, reflect their preferences, reduce burdens on the healthcare system, maintain care quality and preserve resources. However, assessing program effectiveness using observational data is difficult due to confounding by indication and randomized trials may be infeasible. G-estimation provides an analytical framework useful to the assessment of similar programs using observational data.
Postpartum hemorrhage is the most common cause of maternal death. Oxytocin is the standard therapy for the prevention of postpartum hemorrhage, but it requires cold storage, which is not available in many countries. In a large trial, we compared a novel formulation of heat-stable carbetocin with oxytocin.
Gestational trophoblastic neoplasia (GTN) comprises invasive mole (IM), choriocarcinoma(CCM), placental site trophoblastic tumour(PSTT) and epithelioid trophoblastic tumour (ETT). Choriocarcinoma is the most common tumour in this category and is more fatal than the rest. Little is known about GTN in developing countries including the East African region. This study aims to determine the spectrum of GTN affecting thepopulationseekingmanagementinatertiaryhospitalinKenyaandthemortalityratesassociatedwith the disease.
Globally, it is known that HIV-infected pregnant women are prone to depressive symptoms. Research evidences also suggest that nutrient deficiencies may enhance the depressive illness, and that fish oil omega-3 fatty acids may alleviate the depressive symptoms. The aim of this study was to assess the effect of fish oil omega-3 eicosapentaenoic acid-rich supplements on depressive symptoms among HIV-seropositive pregnant women.
We report the main findings of the WHO Multicountry Survey on Maternal and Newborn Health (WHOMCS), which aimed to assess the burden of complications related to pregnancy, the coverage of key maternal health interventions, and use of the maternal severity index (MSI) in a global network of health facilities.
In our cross-sectional study, we included women attending health facilities in Africa, Asia, Latin America, and the Middle East that dealt with at least 1000 childbirths per year and had the capacity to provide caesarean section.